primary rabbit polyclonal anti mkp 1 antibodies Search Results


92
Bio-Techne corporation mkp-1/dusp1 antibody (jj0930)
Mkp 1/Dusp1 Antibody (Jj0930), supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mkp-1/dusp1 antibody (jj0930)/product/Bio-Techne corporation
Average 92 stars, based on 1 article reviews
mkp-1/dusp1 antibody (jj0930) - by Bioz Stars, 2026-02
92/100 stars
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90
Bioworld Antibodies rabbit polyclonal anti-mkp-1
Involvement of <t>MKP-1/ERK1/2</t> pathway in NSC 95397-induced p21 expression and caspase-3 activation in human colon cancer. Representative Western blots showing ( A ) the expression of Cdc25A, the phosphorylation of Cdk1 at Tyr15; ( B ) the expression of MKP-1 and ERK1/2, and the phosphorylation of ERK1/2 at Thr202/Tyr 204 in SW480, SW620, and DLD-1 cells treated with 10 μM NSC 95397 for 6 h, with actin as loading control; ( C ) representative Western blots showing expression of p21 and cleaved caspase-3 in colon cancer cells that were pre-incubated with 20 μM U0126 for 2 h and then treated with 10 m μM NSC 95397 for 6 h.
Rabbit Polyclonal Anti Mkp 1, supplied by Bioworld Antibodies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit polyclonal anti-mkp-1/product/Bioworld Antibodies
Average 90 stars, based on 1 article reviews
rabbit polyclonal anti-mkp-1 - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


Involvement of MKP-1/ERK1/2 pathway in NSC 95397-induced p21 expression and caspase-3 activation in human colon cancer. Representative Western blots showing ( A ) the expression of Cdc25A, the phosphorylation of Cdk1 at Tyr15; ( B ) the expression of MKP-1 and ERK1/2, and the phosphorylation of ERK1/2 at Thr202/Tyr 204 in SW480, SW620, and DLD-1 cells treated with 10 μM NSC 95397 for 6 h, with actin as loading control; ( C ) representative Western blots showing expression of p21 and cleaved caspase-3 in colon cancer cells that were pre-incubated with 20 μM U0126 for 2 h and then treated with 10 m μM NSC 95397 for 6 h.

Journal: International Journal of Molecular Sciences

Article Title: NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway

doi: 10.3390/ijms19061625

Figure Lengend Snippet: Involvement of MKP-1/ERK1/2 pathway in NSC 95397-induced p21 expression and caspase-3 activation in human colon cancer. Representative Western blots showing ( A ) the expression of Cdc25A, the phosphorylation of Cdk1 at Tyr15; ( B ) the expression of MKP-1 and ERK1/2, and the phosphorylation of ERK1/2 at Thr202/Tyr 204 in SW480, SW620, and DLD-1 cells treated with 10 μM NSC 95397 for 6 h, with actin as loading control; ( C ) representative Western blots showing expression of p21 and cleaved caspase-3 in colon cancer cells that were pre-incubated with 20 μM U0126 for 2 h and then treated with 10 m μM NSC 95397 for 6 h.

Article Snippet: The following antibodies were used: rabbit monoclonal anti-p21 (Cell Signaling Technology #2947, Danvers, MA, USA), rabbit monoclonal anti-CDK4 (Cell Signaling Technology #12790), mouse monoclonal anti-CDK6 (Cell Signaling Technology #3136), rabbit polyclonal anti-Phospho-Rb (Ser795) (Cell Signaling Technology #9301), rabbit monoclonal anti-Phospho-Rb (Ser807/811) (Cell Signaling Technology #8516), mouse monoclonal anti-Caspase-9 (Cell Signaling Technology #9608), rabbit monoclonal anti-Cleaved Caspase-9 (Cell Signaling Technology #7237), rabbit monoclonal anti-Caspase-3 (Cell Signaling Technology #9665), rabbit monoclonal anti-Cleaved Caspase-3 (Cell Signaling Technology #9664), rabbit monoclonal anti-Caspase-7 (Cell Signaling Technology #12827), rabbit monoclonal anti-Cleaved Caspase-7 (Cell Signaling Technology #8438), rabbit polyclonal anti-PARP (Cell Signaling Technology #9542), rabbit monoclonal anti-Cleaved PARP (Cell Signaling Technology #5625), rabbit polyclonal anti-cdc25A (Cell Signaling Technology #3652), rabbit polyclonal anti-Phospho-cdc2 (Tyr15) (Cell Signaling Technology #4539), rabbit polyclonal anti-MKP-1 (Bioworld Technology #BS1677, St. Louis Park, MN, USA), rabbit polyclonal anti-ERK1/2 (GeneTex #GTX59618, Irvine, CA, USA), rabbit polyclonal anti-Phospho-ERK1/2 (GeneTex #GTX61126), and mouse monoclonal anti-Actin (Merck Millipore #MAB1501, Burlington, MA, USA).

Techniques: Expressing, Activation Assay, Western Blot, Incubation

A schematic showing that the cytotoxic effect of NSC 95397 on colon cancer cells is activated by inhibiting MKP-1 activity followed by ERK1/2 activation. Lines ending in arrows indicate promotion and T-bars represent inhibition.

Journal: International Journal of Molecular Sciences

Article Title: NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway

doi: 10.3390/ijms19061625

Figure Lengend Snippet: A schematic showing that the cytotoxic effect of NSC 95397 on colon cancer cells is activated by inhibiting MKP-1 activity followed by ERK1/2 activation. Lines ending in arrows indicate promotion and T-bars represent inhibition.

Article Snippet: The following antibodies were used: rabbit monoclonal anti-p21 (Cell Signaling Technology #2947, Danvers, MA, USA), rabbit monoclonal anti-CDK4 (Cell Signaling Technology #12790), mouse monoclonal anti-CDK6 (Cell Signaling Technology #3136), rabbit polyclonal anti-Phospho-Rb (Ser795) (Cell Signaling Technology #9301), rabbit monoclonal anti-Phospho-Rb (Ser807/811) (Cell Signaling Technology #8516), mouse monoclonal anti-Caspase-9 (Cell Signaling Technology #9608), rabbit monoclonal anti-Cleaved Caspase-9 (Cell Signaling Technology #7237), rabbit monoclonal anti-Caspase-3 (Cell Signaling Technology #9665), rabbit monoclonal anti-Cleaved Caspase-3 (Cell Signaling Technology #9664), rabbit monoclonal anti-Caspase-7 (Cell Signaling Technology #12827), rabbit monoclonal anti-Cleaved Caspase-7 (Cell Signaling Technology #8438), rabbit polyclonal anti-PARP (Cell Signaling Technology #9542), rabbit monoclonal anti-Cleaved PARP (Cell Signaling Technology #5625), rabbit polyclonal anti-cdc25A (Cell Signaling Technology #3652), rabbit polyclonal anti-Phospho-cdc2 (Tyr15) (Cell Signaling Technology #4539), rabbit polyclonal anti-MKP-1 (Bioworld Technology #BS1677, St. Louis Park, MN, USA), rabbit polyclonal anti-ERK1/2 (GeneTex #GTX59618, Irvine, CA, USA), rabbit polyclonal anti-Phospho-ERK1/2 (GeneTex #GTX61126), and mouse monoclonal anti-Actin (Merck Millipore #MAB1501, Burlington, MA, USA).

Techniques: Activity Assay, Activation Assay, Inhibition